PNAS/Mechanism of tRNA-mediated +1 ribosomal frameshifting [Biochemistry]
#16174 [ Samuel Hong, S. Sunita, Tatsuy ] 2018-10-30 09:46:28 hit: 8(#f7fff7)
LINK INFOa href="http://www.pnas.org/content/115/44/11226.short?rss=1"
DOI: 10.1073/pnas.1809319115, Accurate translation of the genetic code is critical to ensure expression of proteins with correct amino acid sequences. Certain tRNAs can cause a shift out of frame (i.e., frameshifting) due to imbalances in tRNA concentrations, lack of tRNA modifications or insertions or deletions in tRNAs (called frameshift suppressors). Here, we...