PNAS/Meiosis-specific recombinase Dmc1 is a potent inhibitor of the Srs2 antirecombinase [Biochemistry]

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#16170 [ J. Brooks Crickard, Kyle Kanie ] hit: 8(#f7fff7)


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  DOI: 10.1073/pnas.1810457115
, Cross-over recombination products are a hallmark of meiosis because they are necessary for accurate chromosome segregation and they also allow for increased genetic diversity during sexual reproduction. However, cross-overs can also cause gross chromosomal rearrangements and are therefore normally down-regulated during mitotic growth. The mechanisms that enhance cross-over product formation...