PNAS/Mechanistic insights into GLUT1 activation and clustering revealed by super-resolution imaging [Biochemistry]

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#16087 [ Qiuyan Yan, Yanting Lu, Lulu Z ] hit: 0(#ffffff)


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  DOI: 10.1073/pnas.1803859115
, The glucose transporter GLUT1, a plasma membrane protein that mediates glucose homeostasis in mammalian cells, is responsible for constitutive uptake of glucose into many tissues and organs. Many studies have focused on its vital physiological functions and close relationship with diseases. However, the molecular mechanisms of its activation and transport...