분류:National Academy of Sciences

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SIR proteins create compact heterochromatin fibers [Biochemistry]
DOI: 10.1073/pnas.1810647115, Heterochromatin is a silenced chromatin region essential for maintaining genomic stability and driving developmental processes. The complicated structure and dynamics of heterochromatin have rendered it difficult to char....2018-12-04 09:11:23Sarah G. Swygert, Subhadip Sen

Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-....
DOI: 10.1073/pnas.1816614115, A-kinase anchoring proteins (AKAPs) shape second-messenger signaling responses by constraining protein kinase A (PKA) at precise intracellular locations. A defining feature of AKAPs is a helical region that binds to regu....2018-12-04 09:11:23F. Donelson Smith, Mitchell H.

Design and in vitro realization of carbon-conserving photorespiration [Biochemistry]
DOI: 10.1073/pnas.1812605115, Photorespiration recycles ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) oxygenation product, 2-phosphoglycolate, back into the Calvin Cycle. Natural photorespiration, however, limits agricultural productivity....2018-12-04 09:11:23Devin L. Trudeau, Christian Ed